01 June 2022

NIPT Test in the Diagnostic Lab and its Benefits

The NIPT test is one of the many tests carried out on pregnant women to determine the fetus's condition in the womb as early as possible. Thus, the mother and the future can receive preventive measures earlier.

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In addition to routinely performing ultrasound, the NIPT Test also needs to be carried out to detect the risk of genetic disorders to the chromosomal level by examining DNA fragments in the blood of the prospective mother. What are the mechanisms and benefits? Check out the following explanation.

What is the NIPT Test?

NIPT stands for Non-Invasive Prenatal Test, or an examination to find out crucial information about the baby's health in the womb so expecting parents can monitor the optimal growth and development of the fetus.

NIPT examination can be done from 10 weeks of pregnancy or in the first trimester. You can perform this examination with an easy mechanism and accurate results, and it does not risk harm to the mother's pregnancy.

Aurel Hermansyah also carried out the Non-Invasive Prenatal Test after experiencing a miscarriage. The pubic figure underwent the NIPT Test in the third month of gestation to determine whether there were genetic abnormalities in the fetus. Thus, pregnant women need to do this kind of test as soon as possible.

Aurel underwent an examination at the Diagnostic Lab through a simple procedure of taking a blood sample. Furthermore, the medical team will conduct laboratory tests; the patient waits for the results at home.

Humans have 23 pairs of chromosomes, one of which is the genetic chromosome. These genetic chromosomes determine many things in the baby, such as gender and physical attributes. Examination of the Non-Invasive Prenatal Test can determine if there are missing chromosomes that can affect the health of the prospective baby.

The condition of missing chromosomes or aneuploidy is associated with factors that cause congenital disabilities, such as Down, Edward, and Patau. These conditions can be detected because as much as 5-15% of fetal DNA is carried by the mother's blood which is the sample for the NIPT examination.

Benefits of Doing NIPT Test

The more specific a test is for a health condition, the more accurate the results will be. Like the Non-Invasive Prenatal Test, it also has positive benefits for the mother and the unborn baby; the following are the advantages of doing this examination.

1. Safe

NIPT Test is safe and effective for the examination of fetal chromosomes. There are no side effects even though it is carried out in the first trimester, where generally, the condition of both the mother and baby is still vulnerable because the examination is only carried out by taking 8-10 cc of maternal blood samples only.

2. Ensuring Health Conditions

You can get certainty whether there is a risk of giving birth to a baby with abnormalities or not. Especially for those who missed screening in early pregnancy, it is very necessary to do this test.

3. Without Physical Risk

This test does not cause damage to body tissues because it is non-invasive, so it is safe and will not physically injure the pregnant mother and the fetus.

4. Considering Diagnostic Tests

You can also use the test results as a reference for further examination. For example, if a diagnostic test with more parameters is needed. This is usually done for conditions of growth and development during pregnancy if there are problems.

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5. Suitable for Ages Over 35

It is highly recommended for mothers aged 35 years and over. Another recommended condition is if abnormalities are found from ultrasound readings or there are indications of trisomy abnormalities suffered by the baby.

6. Solutions for Chromosomal Abnormalities in Parents

Parents who have chromosomal abnormalities are recommended to do the NIPT test. Especially for those with a history of Robertsonian translocation, which is a chromosomal break. In general, this condition does not interfere with health but can affect pregnancy and the fetus's condition.

Things to Pay Attention to Before Taking the Test

Although it is safe for the mother and fetus, you need to pay attention to several conditions and considerations before carrying out the NIPT examination. What are the requirements? Check out the following explanation

1. Test Terms

Not obese, not taking blood thinners, not pregnant with twins. This condition must be met before carrying out a series of inspections. In addition, it is necessary to ensure minimum gestational age of 10 weeks.

2. Consultation with a Doctor

It is essential to consult with a gynecologist first. Is it necessary and safe to do the NIPT test, or what is the best recommendation from the doctor in question? Consult what you need to know to know clearly what you need with the current conditions.

3. Cost Factor

Examination costs are high compared to other tests, so you must prepare in advance. This is because the examination is very detailed and related to chromosomes to DNA chains for increased effectiveness and safety.

4. Prepare for Advanced Test

After the first examination is complete, ask your doctor if there are any further tests. In some examinations, some patients still have to do other tests. This is done to obtain the most accurate information related to the health condition of the fetus and the risk of genetic disorders.

Pregnancy is one of the most vulnerable periods in human life, and the prospective baby is being conceived. Therefore, you need to undergo several treatments and examinations to ensure the child is born perfectly, healthy and safe. The Diagnostic Lab, part of the BMHS, is ready to help you perform the NIPT test to monitor your baby's growth and development.

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